3.152 It is vital in a highly competitive global knowledge economy that the UK remains a world leader in science and research. This is why despite fiscal constraints the Government protected science spending and committed to a ring-fenced £4.6 billion science and research budget. Investment in the UK's large scale research facilities (such as the Francis Crick Institute, the Laboratory for Molecular Biology, the Institute of Animal Health and Diamond Synchrotron) in recent years has collectively amounted to about £1 billion of capital investment. Nationally important science and innovation campuses such as at Harwell, Daresbury, Norwich and Babraham have benefited from a further £100 million allocation at Budget 2011. The Government recently committed a further £200 million in science and space over the next three years including £50 million into the development of Graphene and the 2011 Autumn Statement sets out an additional £200 million of funding for science infrastructure.